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KMID : 0352120170320010052
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Journal of Kyung Hee University
2017 Volume.32 No. 1 p.52 ~ p.57
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Anesthetic Management of Pediatric Liver Transplantation for Langerhans Cell Histiocytosis with Central Diabetes Insipidus : A Case Report
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Ryu Seung-Ah
Lee Jae-Hyuk
Lee Chan-Hee
Kim Sun-Key
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Abstract
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A 3-year-old girl with Langerhans cell histiocytosis and central diabetes insipidus underwent liver transplantation under general anesthesia. On arrival at the operating room, she has severe ascites and hypernatremia. During the operation, she showed signs of intravascular volume depletion due to third spacing by ascites and an excessive urine output caused by the central diabetes insipidus. The anesthesiologists endeavored to administer appropriate fluids to optimize the volume status and inhibit too rapid correction of the sodium level. The intraoperative sodium level range was 142-148 mmol/L, and the central venous pressure range was 3-5 mmHg. The operation was completed without complications. Several days after the operation, she was discharged without any significant problem.
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KEYWORD
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Central diabetes insipidus, Langerhans cell histiocytosis, Liver transplantation
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